Symptoms getting worse after physical or mental activity, and possibly taking weeks to get better (also called post-exertional malaise, or PEM)

Experiencing a worsening of symptoms following physical or mental exertion, which may take weeks to improve (known as post-exertional malaise, or PEM), can be linked to several health issues. It is advisable to speak with a healthcare professional if you encounter this symptom.

When to seek medical help

If your symptoms getting worse after physical or mental activity, and possibly taking weeks to get better (also called post-exertional malaise, or pem) is severe, sudden, or accompanied by other concerning symptoms, seek urgent medical attention. Always consult a healthcare professional if you are concerned.

Conditions related to symptoms getting worse after physical or mental activity, and possibly taking weeks to get better (also called post-exertional malaise, or pem)

Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS)

Learn about myalgic encephalomyelitis, also known as chronic fatigue syndrome (ME/CFS). This is a persistent condition that presents a variety of symptoms, with severe fatigue being one of the most prominent.

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