All conditions
Hereditary spastic paraplegia
Hereditary spastic paraplegia refers to a collection of uncommon genetic disorders that lead to weakness and stiffness in the leg muscles. The symptoms tend to worsen gradually over time. This condition is also referred to as familial spastic paraparesis or Strümpell-Lorrain syndrome. Determining the exact number of individuals affected by hereditary spastic paraplegia can be challenging, as it is frequently misdiagnosed. The intensity and development of symptoms can differ significantly between individuals.
Common symptoms:
Hearing loss
A gradual weakness in the legs
Increased muscle tone and stiffness (spasticity)
Problems peeing – such as an urgent need to pee, even when the bladder is not full
A lack of sensation in the feet (sometimes)
Nerve damage in the feet or other extremities ( peripheral neuropathy )
Epilepsy
Problems with balance, co-ordination and speech ( ataxia )
Eye problems – such as damage to the retina (retinopathy) and damage to the optic nerve (optic neuropathy)
Dementia
Ichthyosis – a condition that causes widespread and persistent thick, dry "fish-scale" skin
Learning and developmental problems
Speech, breathing or swallowing problems
Professionals who treat hereditary spastic paraplegia (9)
DJ
Dr James Mackay
Consultant Clinical Genetic Oncologist
Central London
Cancer
Genetics of cancer
Breast cancer
+3
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PS
Professor Sanjay Sharma
Cardiology
Central London
Sports cardiology
Dilated cardiomyopathy
Sudden death
+3
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DA
Dr Arvind Chandratheva
Neurology
Central London
Stroke
Neurological disorders
Neurorehabilitation
+3
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PG
Professor Gerald Carr-White
Cardiology
SE1 South Bank London
Heart failure
Dilated cardiomyopathy
Hypertrophic cardiomyopathy
+3
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DA
Dr Amanda Varnava
Cardiology
Central London
Palpitations
Syncope
Hypertension (high blood pressure)
+3
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DC
Dr Carla Cordivari
Consultant Neurophysiologist
Central London
Spasticity
Botulinum toxin (Botox™)
Movement disorders
+3
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PC
Professor Christoph Nienaber
Cardiology
W1G Marylebone London
Coronary angiography and invasive cardiology
Aortic valve replacement
Aortic valve replacement (minimally invasive)
+3
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DR
Dr Rachel Farrell
Neurology
Central London
Neurological disorders
Neurorehabilitation
Multiple sclerosis
+3
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MV
Mr Vikas Acharya
Consultant Rhinologist, Facial Plastic and ENT Surgeon
Bushey
Blocked nose
Rhinitis
Sinusitis
+5
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