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Hereditary spastic paraplegia

Hereditary spastic paraplegia refers to a collection of uncommon genetic disorders that lead to weakness and stiffness in the leg muscles. The symptoms tend to worsen gradually over time. This condition is also referred to as familial spastic paraparesis or Strümpell-Lorrain syndrome. Determining the exact number of individuals affected by hereditary spastic paraplegia can be challenging, as it is frequently misdiagnosed. The intensity and development of symptoms can differ significantly between individuals.